試題詳解

35. A 62-year-old man with a history of long-standing ulcerative colitis presents with increasing
bdominal pain and weight loss. Colonoscopy reveals a mass in the sigmoid colon. Compared with sporadic colon adenocarcinoma, which feature is more likely in colitis-associated carcinoma?
(A) invariably right-sided and exophytic
(B) Has a negligible risk of synchronous tumors
(C) Arises from flat dysplasia with multifocal lesions
(D) Shows fewer p53 mutations than sporadic cases