試題詳解

34.A 34-year-old woman presents with a 3-week history of fever, night sweats, and painless cervical lymphadenopathy. Excisional biopsy shows nodular architecture with large Reed-Sternberg cells in a
background of small lymphocytes, histiocytes, and eosinophils. Immunostaining shows CD15-positive, CD30-positive, CD45-negative large cells. Which diagnosis is most likely?
(A) Diffuse large B-cell lymphoma
(B) Classical Hodgkin lymphoma, nodular sclerosis or mixed cellularity type
(C) Reactive follicular hynernlasis
(D) Nodular lymphocyte-predominant Hodgkin lymphoma