試題詳解

33. A marathon runner is engaged in a 42-km race. At this stage, there is a massive flux of fatty acids entering the ẞ-oxidation status. Which of the following statements regarding this regulatory transition is      NOT      correct?
(A) Elevated levels of glucagon activate protein kinases that phosphorylate and inactivate acetyl-CoA carboxylase.
(B) An increase in the cellular AMP/ATP ratio activates AMP-activated protein kinase, which further suppresses the formation of malonyl-CoA.
(C) The allosteric inhibition of carnitine acyltransferase I is further relieved.
(D) The change of malonyl-CoA levels allows for the translocation of acetyl-CoA to compromise the situation.
(E) Enhanced fatty acyl-CoA flux increases reliance on the carnitine shuttle for translocation.