試卷名稱:115年 - [無官方正解]115 國立臺灣大學_ 碩士班招生考試試題:生物化學(一般生物化學)#137622
年份:115年
科目:研究所、轉學考(插大)◆生物化學
22. G-protein coupled receptors (GPCRs) utilize different mechanisms for desensitization. What is the specific role of beta-arrestin in the termination of GPCR signaling?
(A) It hydrolyzes cAMP to 5'-AMP to reduce second messenger levels.
(B) It acts as a Guanine Nucleotide Exchange Factor (GEF) for the alpha-subunit.
(C) It dephosphorylates the receptor to restore its basal state.
(D) It sterically delays G-protein coupling and facilitates clathrin-mediated endocytosis.
(E) It phosphorylates the Ga subunit to accelerate GTP hydrolysis.